GPR42 Polyclonal Antibody, 50ul Cell Function Analysis Defects in PEX3 are a

Defects in PEX3 are a cause Zellweger syndrome (ZWS)

The protein encoded belongs to the collectin family and is an important element in the innate immune system

Mutations in PHYKPL (5-phosphohydroxy-L-lysine phospho-lyase) may cause phosphohydroxylysinuria

This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain

GPR42 Polyclonal Antibody, 50ul Cell Function Analysis Defects in PEX3 are aGPR42, also named as GPR42P, FFAR1L and GPR41L, belongs to the G protein coupled receptor 1 family. GPR42 appears to have arisen by tandem duplication of FFAR3 and have lost the ability to activate G protein family in respose to carboxylate ligands primarily due to an amino acid change at position 174. It is an orphan receptor.