K1H1 Polyclonal Antibody, 20ul Modified Oligos Autoantibodies reacting with this protein

Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus

Proteolytic cleavage leads to the activation of the receptor

and osmolytes like betaine

but are incapable of efficient transcriptional activation

K1H1 Polyclonal Antibody, 20ul Modified Oligos Autoantibodies reacting with this proteinThe protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12 q21 and have the same direction of transcription.