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Nephrin Polyclonal Antibody, 20ul Miscellaneous The expression of this receptor

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Nephrin Polyclonal Antibody, 20ul Miscellaneous The expression of this receptorNPHS1 encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. NPHS1 is primarily expressed in renal tissues, and the protein is a type 1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this

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Description

The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors

The product of this gene contains several domains similar to von Willebrand Factor type A domains

endonuclease G-like) catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain

including differentiation and migration of neuronal stem cells

Nephrin Polyclonal Antibody, 20ul Miscellaneous The expression of this receptorNPHS1 encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. NPHS1 is primarily expressed in renal tissues, and the protein is a type 1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this

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