WNK1 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos Deletions that remove the entire

Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities

Enriched expression of this gene in embryonic mouse brain suggests that this gene may play a role in nervous system development

The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks

Guanine nucleotide exchange factors (GEFs)

WNK1 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos Deletions that remove the entireWNK1 encodes a member of the WNK subfamily of serine threonine protein kinases. The serine threonine protein kinase WNK1 may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full length