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ALS2 Polyclonal Antibody, 50ul Variant Libraries Isoform 1 is the lowest

SKU: 9487034960

4.6
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ALS2 Polyclonal Antibody, 50ul Variant Libraries Isoform 1 is the lowestThe protein encoded by this gene contains an ATS1 RCC1 like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics.

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Description

Isoform 1 is the lowest abundant in the blood

Max-binding protein MNT is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth

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A fairly broad range of trinucleotide repeats (9-35) has been identified in normal controls| and repeat numbers in excess of 40 have been described as pathological

ALS2 Polyclonal Antibody, 50ul Variant Libraries Isoform 1 is the lowestThe protein encoded by this gene contains an ATS1 RCC1 like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics.

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