Socius Polyclonal Antibody, 100ul Modified Oligos In contrast to the rodent

In contrast to the rodent orthologous protein

Belongs to the Mediator complex subunit 31 family

The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used

and is associated with several disease states including cancer and Alzheimer's disease

Socius Polyclonal Antibody, 100ul Modified Oligos In contrast to the rodentUBXN11 (UBX domain protein 11) encodes a protein with a divergent C terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C terminal region. It also interacts with several heterotrimeric G proteins through their G alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity