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CD6 Polyclonal Antibody, 100ul[BT-AP01975] Metabolic enzymes Mutations in this gene cause

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CD6 Polyclonal Antibody, 100ul[BT-AP01975] Metabolic enzymes Mutations in this gene causeCLIC6 (chloride intracellular channel 6) encodes a member of the chloride intracellular channel family of proteins. CLIC6 is part of a large triplicated region found on chromosomes 1, 6, and 21. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Description

Mutations in this gene cause thyroid dyshormonogenesis

Expressed at higher level in muscle and heart compared to brain

resulting in repression of MEF2-dependent genes

as well as KRTHB3 and KRTHB6

CD6 Polyclonal Antibody, 100ul[BT-AP01975] Metabolic enzymes Mutations in this gene causeCLIC6 (chloride intracellular channel 6) encodes a member of the chloride intracellular channel family of proteins. CLIC6 is part of a large triplicated region found on chromosomes 1, 6, and 21. Alternative splicing results in multiple transcript variants encoding different isoforms.

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