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MuSK(Phospho Tyr755) Polyclonal Antibody, 100ul Immune Cell Analysis function:Transcriptional repressor which preferentially binds

SKU: 95908416364

4.2
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MuSK(Phospho Tyr755) Polyclonal Antibody, 100ul Immune Cell Analysis function:Transcriptional repressor which preferentially bindsThis gene encodes a muscle specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described.

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Description

function:Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF

This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs)

Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia

Neuropilins bind many ligands and various types of co-receptors

MuSK(Phospho Tyr755) Polyclonal Antibody, 100ul Immune Cell Analysis function:Transcriptional repressor which preferentially bindsThis gene encodes a muscle specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described.

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