Mnk1 Polyclonal Antibody, 20ul[BT-AP05493] Antibody Development The protein localizes primarily to

The protein localizes primarily to the nucleus and its expression is developmentally regulated

This protein plays a role in the regulation of several cellular processes

kidney reabsorption

Alterations in this gene may also be associated with Crohn's disease

Mnk1 Polyclonal Antibody, 20ul[BT-AP05493] Antibody Development The protein localizes primarily toMKNK1 (MAP kinase interacting serine threonine kinase 1) encodes a Ser Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C terminal region of eIF4G. Alternatively spliced transcript variants have been noted for MKNK1.