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TNPO1 Polyclonal Antibody, 100ul Enzymes Phosphorylation by protein kinase C

SKU: 96137900744

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TNPO1 Polyclonal Antibody, 100ul Enzymes Phosphorylation by protein kinase CThis gene encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins.

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Description

Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane| leading to its presence in the cytoplasm

Favors Hoogsteen base-pairing in the active site

This PTP was shown to specially interact with BMX/ETK

Polymorphisms in this gene may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome

TNPO1 Polyclonal Antibody, 100ul Enzymes Phosphorylation by protein kinase CThis gene encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins.

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