Ikaros 3 Polyclonal Antibody, 50ul Bottle-Top Dispenser Catalytic activity:NAD(+) + (ADP-D-ribosyl)(n)-acceptor =

Catalytic activity:NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor

They may also play a role in intracellular transport to axons and dendrites

Belongs to the krueppel C2H2-type zinc-finger protein family

The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway

Ikaros 3 Polyclonal Antibody, 50ul Bottle-Top Dispenser Catalytic activity:NAD(+) + (ADP-D-ribosyl)(n)-acceptor =IKZF3 encodes a member of the Ikaros family of zinc finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic specific transcription factors involved in the regulation of lymphocyte development. Zinc finger protein Aiolos is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of