LAX1 Polyclonal Antibody, 100ul Biochemical Reagents a pseudogene of SRSF11 has

a pseudogene of SRSF11 has been found on chromosome 12

This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB

Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein

Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins

LAX1 Polyclonal Antibody, 100ul Biochemical Reagents a pseudogene of SRSF11 hasNegatively regulates TCR (T cell antigen receptor) mediated signaling in T cells and BCR (B cell antigen receptor) mediated signaling in B cells.,induction: Up regulated in T cells following TCR engagement.,PTM: Phosphorylated on tyrosines by Syk, Lck or ZAP70 upon TCR or BCR activation; which leads to the recruitment of GRB2, PIK3R1 and GRAP2.,subunit: When phosphorylated, interacts with GRB2, PIK3R1 and GRAP2.,tissue specificity: Expressed in