Rat 5-Hydroxytryptamine Receptor 2B, HTR2B ELISA Kit, 96T Protein Post-translational Modification Two uORFs in the 5'

Two uORFs in the 5' UTR negatively regulate the expression and activity of the encoded protein

Proteins modified in this way

Functions as an inhibitor of the early TH1 cytokine response

and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis

Rat 5-Hydroxytryptamine Receptor 2B, HTR2B ELISA Kit, 96T Protein Post-translational Modification Two uORFs in the 5'G protein coupled receptor for 5 hydroxytryptamine (serotonin) (PubMed: 1505525, PubMed: 1331748). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances (PubMed: 22525520). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide binding proteins (G proteins) and modulates the activity of down stream effectors (PubMed: 1505525, PubMed: 1331748). Beta arrestin family members