PDE1A Polyclonal Antibody, 50ul Micro Centrifuge Tubes A related pseudogene has been

A related pseudogene has been identified on chromosome 4

It is involved in mammalian pigmentation

MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain

RAB3GAP2 has the highest level of expression in the brain

PDE1A Polyclonal Antibody, 50ul Micro Centrifuge Tubes A related pseudogene has beenCyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and or cGMP to their respective nucleoside 5 prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+) calmodulin (see CALM1; MIM 114180) dependent PDEs (CaM PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001