Rb Polyclonal Antibody, 50ul[BT-AP07689] Roller Bottles Defects in this gene are

Defects in this gene are a cause of susceptibility to familial hypertrigliceridemia

In addition to possessing several cell adhesion molecule-like domains

This receptor appears to bind the majority of beta-chemokine family members

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Rb Polyclonal Antibody, 50ul[BT-AP07689] Roller Bottles Defects in this gene areRB transcriptional corepressor 1 encoded by RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.