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PKC Theta Polyclonal Antibody, 20ul[BT-AP07222] Inoculating Loops/Needles The amino terminus of calreticulin

SKU: 97197487900

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PLN111.00 PLN146.00

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PKC Theta Polyclonal Antibody, 20ul[BT-AP07222] Inoculating Loops/Needles The amino terminus of calreticulinProtein kinase C (PKC) is a family of serine and threonine specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile

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Description

The amino terminus of calreticulin interacts with the DNA-binding domain of the glucocorticoid receptor and prevents the receptor from binding to its specific glucocorticoid response element

Substrates include anticancer drugs such as vinblastine

also known as PUMAG or Puma-g

and a C-terminal extracellular region with four N-glycosylation sites

PKC Theta Polyclonal Antibody, 20ul[BT-AP07222] Inoculating Loops/Needles The amino terminus of calreticulinProtein kinase C (PKC) is a family of serine and threonine specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile

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