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MYO1A Polyclonal Antibody, 100ul Serological Pipets Hypermethylation and transcriptional downregulation of

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MYO1A Polyclonal Antibody, 100ul Serological Pipets Hypermethylation and transcriptional downregulation ofThis gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional skeletal muscle myosin 1 (MYH1). Unconventional myosins contain the basic domains characteristic of conventional myosins and are further distinguished from class members by their tail domains. They function as actin based molecular motors. Mutations in this gene have been associated with autosomal

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Description

Hypermethylation and transcriptional downregulation of this gene has been observed in oligodendroglial tumors with deletions of chromosomal arms 1p and 19q

and may play a role in the blood-brain barrier system

Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains

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MYO1A Polyclonal Antibody, 100ul Serological Pipets Hypermethylation and transcriptional downregulation ofThis gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional skeletal muscle myosin 1 (MYH1). Unconventional myosins contain the basic domains characteristic of conventional myosins and are further distinguished from class members by their tail domains. They function as actin based molecular motors. Mutations in this gene have been associated with autosomal

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