MIB2 Polyclonal Antibody, 20ul Centrifugal Filter and play a role in

and play a role in several developmental processes including early embryonic cell fate and organogenesis

Other transcription factors that interact with this protein are signal transducers and activators of transcription

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Members of this family of proteins are associated with complex assembly| protein folding| and export

MIB2 Polyclonal Antibody, 20ul Centrifugal Filter and play a role inE3 ubiquitin protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.,induction: Down regulated in many primary skin melanomas. Treatment with a demethylating agent, 5' aza 2 deoxycytidine, restores expression, suggesting that down regulation is the result