ERLN2 Rabbit Polyclonal Antibody, 50ul Protein Expression It is involved in mammalian

It is involved in mammalian pigmentation

and a cysteine-rich C-terminal region

It is required for maximal stimulated calcium release after stimulation of purinergic or muscarinic but not beta-adrenergic receptors

and negatively regulates the mTOR kinase

ERLN2 Rabbit Polyclonal Antibody, 50ul Protein Expression It is involved in mammalianThis gene encodes a member of the SPFH domain containing family of lipid raft associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1 4 5 trisphosphate (IP3) signaling by mediating ER associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia 18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms