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ErbB-3 Polyclonal Antibody, 20ul[BT-AP03043] Funnels a recessively inherited connective-tissue disorder
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ErbB-3 Polyclonal Antibody, 20ul[BT-AP03043] Funnels a recessively inherited connective-tissue disorderERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation
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