Rad52(Phospho Tyr104) Polyclonal Antibody, 100ul Cryopreservation LRP11 (low density lipoprotein receptor-related

LRP11 (low density lipoprotein receptor-related protein 11)

Several transcript variants encoding different protein isoforms have been found for this gene

Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy)

a calcium-binding EF hand and a divergent SH2 domain

Rad52(Phospho Tyr104) Polyclonal Antibody, 100ul Cryopreservation LRP11 (low density lipoprotein receptor-relatedThe protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double strand break repair and homologous recombination. This gene product was shown to bind single stranded DNA ends, and mediate the DNA DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA