PPIL1 Rabbit Polyclonal Antibody, 50ul Endonucleases & Exonucleases The expression of UGDH is

The expression of UGDH is up-regulated by transforming growth factor beta and down-regulated by hypoxia

Disruption of this gene has been correlated with the autosomal dominant Marie Unna hereditary hypotrichosis disease

Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4

Until 2010

PPIL1 Rabbit Polyclonal Antibody, 50ul Endonucleases & Exonucleases The expression of UGDH isThis gene is a member of the cyclophilin family of peptidylprolyl isomerases (PPIases). The cyclophilins are a highly conserved ubiquitous family members of which play an important role in protein folding immunosuppression by cyclosporin A and infection of HIV 1 virions. Based on similarity to other PPIases this protein could accelerate the folding of proteins and might catalyze the cis trans isomerization of proline imidic peptide bonds in