TOPRS Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) 2000 [PubMed 10888605])

2000 [PubMed 10888605])

Mutations in this gene have been associated with microencephaly| cortical malformations| and mental retardation

A translocation involving FOXO4 on chromosome X and the homolog of the Drosophila trithorax gene

ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences

TOPRS Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) 2000 [PubMed 10888605])This gene encodes a nuclear protein which is serine and arginine rich, and contains a RING type zinc finger domain. It is highly expressed in the testis, and functions as an ubiquitin protein E3 ligase. Mutations in this gene are associated with retinitis pigmentosa type 31. Alternatively spliced transcript variants, encoding different isoforms, have been observed for this locus.