UBA2 Polyclonal Antibody, 100ul Miscellaneous Mutations affecting this gene are

Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIG

a novel anti-convulsant drug

These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme

This protein contains a Guanine nucleotide exchange factor (GEF) domain which is necessary for its role in growth and differentiation

UBA2 Polyclonal Antibody, 100ul Miscellaneous Mutations affecting this gene arePosttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO activating enzyme for the sumoylation of proteins.