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PRDM3 Polyclonal Antibody, 100ul Nucleic Acid Amplification Four isoforms of CABC1 exist

SKU: 99659162117

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SEK123.75 SEK147.75

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PRDM3 Polyclonal Antibody, 100ul Nucleic Acid Amplification Four isoforms of CABC1 existPRDM3 can be produced either as a separate transcript and as a fusion transcript with EVI1. A chromosomal aberration involving PRDM3 is found in a form of acute myeloid leukemia. The myelodysplastic syndromes (MDS, formerly known as "preleukemia") are a diverse collection of hematological conditions united by ineffective production of blood cells and varying risks of transformation to acute myelogenous leukemia.

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Description

Four isoforms of CABC1 exist due to alternative splicing events

Granzyme H is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells

SF3B3 encodes subunit 3 of the splicing factor 3b protein complex

PLD1 (phospholipase D1) encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline

PRDM3 Polyclonal Antibody, 100ul Nucleic Acid Amplification Four isoforms of CABC1 existPRDM3 can be produced either as a separate transcript and as a fusion transcript with EVI1. A chromosomal aberration involving PRDM3 is found in a form of acute myeloid leukemia. The myelodysplastic syndromes (MDS, formerly known as "preleukemia") are a diverse collection of hematological conditions united by ineffective production of blood cells and varying risks of transformation to acute myelogenous leukemia.

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