Tcl1 Polyclonal Antibody, 20ul Immunology heart and placenta

heart and placenta

The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta

This protein binds to an extended groove that is formed by the interaction of CBF1

subcellular location:Colocalizes with RAD51 to multiple nuclear foci

Tcl1 Polyclonal Antibody, 20ul Immunology heart and placentaOverexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T cell antigen receptor (TCR) alpha (MIM 186880) or TCR beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998