Laminin-R Polyclonal Antibody, 100ul Thermal Control Defects in this gene can

Defects in this gene can result in three different disorders

which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins

also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4)

O-glycanase digest suggests mucin-type glycosylation (done in HB-EGF purified from histiocytic lymphoma cell line U-937)

Laminin-R Polyclonal Antibody, 100ul Thermal Control Defects in this gene canLaminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non