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SBE13 onazole D8 InChi: InChI=1S/C22H24N2O2/c25-22-18(14-24-11-4-5-12-24)13-19(20-9-6-10-23-21(20)22)16-26-15-17-7-2-1-3-8-17/h1-3

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4.3
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SBE13 onazole D8 InChi: InChI=1S/C22H24N2O2/c25-22-18(14-24-11-4-5-12-24)13-19(20-9-6-10-23-21(20)22)16-26-15-17-7-2-1-3-8-17/h1-3SBE13 is a potent and selective Plk1 inhibitor, with an IC50 of 200 pM; SBE13 poorly inhibits Plk2 (IC50>66 M) or Plk3 (IC50=875 nM). Product information CAS Number: 775294 82 1 Molecular Weight: 442. 94 Formula: C24H27ClN2O4 Synonym: SBE 13 Chemical Name: ({4 [(6 chloropyridin 3 yl)methoxy] 3 methoxyphenyl}methyl)[2 (3,4 dimethoxyphenyl)ethyl]amine Smiles: COC1=CC=C(CCNCC2C=C(OC)C(=CC=2)OCC2=CN=C(Cl)C=C2)C=C1OC InChiKey: XNPRQBVQOJZMMA UHFFFAOYSA N

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Description

InChi: InChI=1S/C22H24N2O2/c25-22-18(14-24-11-4-5-12-24)13-19(20-9-6-10-23-21(20)22)16-26-15-17-7-2-1-3-8-17/h1-3

13-tetraoxo-3

characteristic of apoptosis: a brightblue fluorescent condensed nuclei seen through a fluorescence microscope after Hoechst 33258-staining

Smiles: CC1C=CC(=CC=1)NC1=CC(=O)C2SC(C)=NC=2C1=O

SBE13 onazole D8 InChi: InChI=1S/C22H24N2O2/c25-22-18(14-24-11-4-5-12-24)13-19(20-9-6-10-23-21(20)22)16-26-15-17-7-2-1-3-8-17/h1-3SBE13 is a potent and selective Plk1 inhibitor, with an IC50 of 200 pM; SBE13 poorly inhibits Plk2 (IC50>66 M) or Plk3 (IC50=875 nM). Product information CAS Number: 775294 82 1 Molecular Weight: 442. 94 Formula: C24H27ClN2O4 Synonym: SBE 13 Chemical Name: ({4 [(6 chloropyridin 3 yl)methoxy] 3 methoxyphenyl}methyl)[2 (3,4 dimethoxyphenyl)ethyl]amine Smiles: COC1=CC=C(CCNCC2C=C(OC)C(=CC=2)OCC2=CN=C(Cl)C=C2)C=C1OC InChiKey: XNPRQBVQOJZMMA UHFFFAOYSA N

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