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AY 77 Size:10mg solid 15-tetrahydroxy-6'-[(1Z)-2-hydroxy-1-propen-1-yl]-5'

SKU: 12176847408

4.9
USD727.50 USD777.50

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AY 77 Size:10mg solid 15-tetrahydroxy-6'-[(1Z)-2-hydroxy-1-propen-1-yl]-5'AY 77 is a potent PAR2 biased agonist. AY 77 exhibits bias for Ca2+ over ERK1 2 signaling (EC50 values are 40 nM for Ca2+ release versus 2 M for ERK1 2 phosphorylation). Shows selectivity for PAR2 over PAR1. Promotes migration of human breast cancer cells in vitro. Product information CAS Number: 1835734 92 3 Molecular Weight: 404. 50 Formula: C21H32N4O4 Synonym: AY77 AY 77 Isox Cha Chg NH2 Chemical Name: N ((S) 1 (((S) 2 amino 1 cyclohexyl 2

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Description

15-tetrahydroxy-6'-[(1Z)-2-hydroxy-1-propen-1-yl]-5'

A Negative Allosteric Modulator of WNT Receptor Frizzled 4 Switches into an Allosteric Agonist

4-dichlorobenzylidene)piperidin-4-one

InChiKey: KRIKILRRJCIWNB-UHFFFAOYSA-N

AY 77 Size:10mg solid 15-tetrahydroxy-6'-[(1Z)-2-hydroxy-1-propen-1-yl]-5'AY 77 is a potent PAR2 biased agonist. AY 77 exhibits bias for Ca2+ over ERK1 2 signaling (EC50 values are 40 nM for Ca2+ release versus 2 M for ERK1 2 phosphorylation). Shows selectivity for PAR2 over PAR1. Promotes migration of human breast cancer cells in vitro. Product information CAS Number: 1835734 92 3 Molecular Weight: 404. 50 Formula: C21H32N4O4 Synonym: AY77 AY 77 Isox Cha Chg NH2 Chemical Name: N ((S) 1 (((S) 2 amino 1 cyclohexyl 2

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