PEAQX Catalog No.:M8604-2 AS2034178 was dosed to normal

AS2034178 was dosed to normal mice and Zucker fatty rats under fasting conditions for oral glucose tolerance test via oral gavage at 3-10 mg/kg

PubMed Central PMCID: PMC4844649

Molecular Weight: 539

Genz-123346 and a few other GCS inhibitors are substrates for multi-drug resistance efflux pumps such as P-gp (ABCB1

PEAQX Catalog No.:M8604-2 AS2034178 was dosed to normalPEAQX, also known as NVP AAM077; is a competitive antagonist at the NMDA receptor. Although originally described as 100 fold selective for GluN1 GluN2A receptors vs. GluN1 GluN2B receptors, more detailed studies of the Ki of PEAQX revealed it only shows a 5 fold difference in affinity for GluN1 GluN2A vs. GluN1 GluN2B receptors. It is also a potent anticonvulsant in animal tests. Product information CAS Number: 459836 30 7 Molecular Weight: 454. 21