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MDV-3100 - CAS# 915087-33-1 60135 is an allosteric inhibitor of

MDV-3100 - CAS# 915087-33-1 60135 is an allosteric inhibitor of

Name: MDV-3100 - CAS# 915087-33-1 60135 is an allosteric inhibitor of
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MDV-3100 - CAS# 915087-33-1 60135 is an allosteric inhibitor ofEnzalutamide, also known as MDV3100, CAS No. 915087 33 1, is an orally bioavailable, organic, non steroidal small molecule targeting the androgen receptor (AR) with potential antineoplastic activity. Through a mechanism that is reported to be different from other approved AR antagonists, selective androgen receptor modulator MDV3100 inhibits the activity of prostate cancer cell ARs, which may result in a reduction in prostate cancer cell proliferation

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Description

is an allosteric inhibitor of Bcr-abl tyrosine kinase activity (IC50 = 267 nM)

Pizarro JG

257 and 200 nM in vitro cytotoxicity assay

Molecular Weight: 1415

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