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TBK1 PROTAC® 3i - CAS# 2052306-13-3 size:2mg solid pharmaceutically acceptable salts thereof and

SKU: 27622842219

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TBK1 PROTAC® 3i - CAS# 2052306-13-3 size:2mg solid pharmaceutically acceptable salts thereof andTBK1 PROTAC 3i, CAS No. 2052306 13 3, is a Potent TANK binding kinase 1 (TBK1) Degrader. It exhibits >50 fold selectivity for TBK1 over the closely related IKK. It comprises a ligand for von Hippel Lindau (VHL) protein joined by a linker to a TBK1 targeting moiety. It brings about near complete degradation of TBK1 in mutant K Ras and wild type cancer cell lines with no significant effect of proliferation. Product information CAS Number: 2052306 13 3

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Description

pharmaceutically acceptable salts thereof and compositions containing said inhibitors for prophylaxis and treatment of viral diseases

Perkins MM

Convergence of Wnt and Notch signaling controls ovarian cancer cell survival

Sperlich J

TBK1 PROTAC® 3i - CAS# 2052306-13-3 size:2mg solid pharmaceutically acceptable salts thereof andTBK1 PROTAC 3i, CAS No. 2052306 13 3, is a Potent TANK binding kinase 1 (TBK1) Degrader. It exhibits >50 fold selectivity for TBK1 over the closely related IKK. It comprises a ligand for von Hippel Lindau (VHL) protein joined by a linker to a TBK1 targeting moiety. It brings about near complete degradation of TBK1 in mutant K Ras and wild type cancer cell lines with no significant effect of proliferation. Product information CAS Number: 2052306 13 3

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