Zonisamide D-1186 2016 Oct 20

2016 Oct 20

RS-127445 administrated at dose of 5 mg/kg with approximately 60% of an intraperitoneal dose and 14% of the oral dose is bioavailable

2) and antagonized the dopamine induction of [(35)S]GTPgammaS binding (pA2=9

It is on the World Health Organization's List of Essential Medicines

Zonisamide D-1186 2016 Oct 20Zonisamide is a sulfonamide anticonvulsant approved for use as an adjunctive therapy in adults with partial onset seizures; infantile spasm, mixed seizure types of LennoxGastaut syndrome, myoclonic, and generalized tonic clonic seizure. Product information CAS Number: 68291 97 4 Molecular Weight: 212. 23 Formula: C8H8N2O3S Chemical Name: (1,2 benzoxazol 3 yl)methanesulfonamide Smiles: NS(=O)(=O)CC1=NOC2=CC=CC=C21 InChiKey: UBQNRHZMVUUOMG UHFFFAOYSA N