Maribavir 204 310(2):391-7

310(2):391-7

1007/s00404-013-2977-7

Outgrowth of drug-resistant carcinomas expressing markers of tumor aggression after long-term TβRI/II kinase inhibition with LY2109761

but it failed to do so in healthy volunteers during Phase I clinical trials

Maribavir 204 310(2):391-7Maribavir, also known as 1263W 94; BW 1263W 94; GW 1263; GW 257406X; SHP 620; VP 41263; BW 1263W94, is an UL97 kinase inhibitor potentially for the treatment of cytomegalovirus (CMV) infection. The mechanism by which maribavir inhibits HCMV replication is by inhibition of an HCMV encoded protein kinase enzyme called UL97 or pUL97. Product information CAS Number: 176161 24 3 Molecular Weight: 376. 24 Formula: C15H19Cl2N3O4 Chemical Name: (2S,3S,4R,5S)