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Acalabrutinib - CAS# 1420477-60-6 size:10mg solid KDM5-C70 was used at 1-10

Acalabrutinib - CAS# 1420477-60-6 size:10mg solid KDM5-C70 was used at 1-10

Name: Acalabrutinib - CAS# 1420477-60-6 size:10mg solid KDM5-C70 was used at 1-10
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Acalabrutinib - CAS# 1420477-60-6 size:10mg solid KDM5-C70 was used at 1-10Acalabrutinib, also known as ACP 196, CAS No. 1420477 60 6, is an orally available inhibitor of Brutons tyrosine kinase (BTK) with potential antineoplastic activity. Upon administration, ACP 196 inhibits the activity of BTK and prevents the activation of the B cell antigen receptor (BCR) signaling pathway. This prevents both B cell activation and BTK mediated activation of downstream survival pathways. This leads to an inhibition of the growth of

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Description

KDM5-C70 was used at 1-10 µM in vitro and cellular assays

InChi: InChI=1S/C12H21N3O2/c1-2-3-4-5-6-7-8-13-10-9-11(16)15-12(17)14-10/h9H

Molecular Weight: 323

in the in vitro signaling assay on primary human CLL cells

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