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BMS-707035 - CAS# 729607-74-3 526 SE Lomitapid is a novel agent

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BMS-707035 - CAS# 729607-74-3 526 SE Lomitapid is a novel agentBMS 707035 is a potent, specific, and reversible HIV I integrase (IN) inhibitor that blocks HIV IN strand transfer activity IC50 of 15 nM. BMS 707035 binding affinity to IN is also affected by the four terminal bases at the 5 end of the pre processed U5 long terminal repeat (LTR). Product information CAS Number: 729607 74 3 Molecular Weight: 410. 42 Formula: C17H19FN4O5S Synonym: BMS 707035 BMS707035 Chemical Name: 2 (1,1 dioxo 1,2 thiazinan 2 yl) N

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Description

Lomitapid is a novel agent for the treatment of homozygous familial hypercholesterolemia

It reduces mean arterial blood pressure by decreasing systemic vascular resistance

InChi: InChI=1S/C28H30O6/c1-11(2)21-15-7-13(5)23(25(31)17(15)9-19(29)27(21)33)24-14(6)8-16-18(26(24)32)10-20(30)28(34)22(16)12(3)4/h7-12

Chemical Name: 1-({4-[2-(azepan-1-yl)ethoxy]phenyl}methyl)-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol

BMS-707035 - CAS# 729607-74-3 526 SE Lomitapid is a novel agentBMS 707035 is a potent, specific, and reversible HIV I integrase (IN) inhibitor that blocks HIV IN strand transfer activity IC50 of 15 nM. BMS 707035 binding affinity to IN is also affected by the four terminal bases at the 5 end of the pre processed U5 long terminal repeat (LTR). Product information CAS Number: 729607 74 3 Molecular Weight: 410. 42 Formula: C17H19FN4O5S Synonym: BMS 707035 BMS707035 Chemical Name: 2 (1,1 dioxo 1,2 thiazinan 2 yl) N

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