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LY2109761 - TGFβ Inhibitor. CAS# 700874-71-1 size:Contact sales@xcessbio.com for quotation leukemia (MV-4-11)

LY2109761 - TGFβ Inhibitor. CAS# 700874-71-1 size:Contact [email protected] for quotation leukemia (MV-4-11)

Name: LY2109761 - TGFβ Inhibitor. CAS# 700874-71-1 size:Contact sales@xcessbio.com for quotation leukemia (MV-4-11)
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SKU: 35563961699
Price: 68.00 USD
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SKU: 35563961699

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LY2109761 - TGFβ Inhibitor. CAS# 700874-71-1 size:Contact [email protected] for quotation leukemia (MV-4-11)LY2109761, CAS No. 700874 71 1, is a highly potent and selective TGF receptor type I and type II (TRI II) inhibitor with Ki of 38 nM and 300 nM respectively. Blocking TRI II kinase activity with LY2109761 completely suppresses both the basal and TGF 1 stimulated migration and invasion of L3. 6pl GLT cells, and completely suppresses TGF induced Smad2 phosphorylation. LY2109761 treatment at 1 nM is sufficient to significantly block the migration and

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Description

leukemia (MV-4-11)

CXCL1 concentration in the serum peaking at 3 h after the injection

Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death

2014 Feb 10

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