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EXP3174 - CAS# 124750-92-1 Catalog No.:M6459-2 both of which are critical

EXP3174 - CAS# 124750-92-1 Catalog No.:M6459-2 both of which are critical

Name: EXP3174 - CAS# 124750-92-1 Catalog No.:M6459-2 both of which are critical
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EXP3174 - CAS# 124750-92-1 Catalog No.:M6459-2 both of which are criticalEXP3174, also known as Losartan Carboxylic Acid, CAS No. 124750 92 1, is a physiologically active metabolite of losartan, produced by cytochrome P450 isoforms in the liver. Like the parent compound, EXP3174 is a potent AT1 antagonist (Kis = 0. 57 and 0. 67 nM for rat and human forms, respectively), producing a depressor response and vasodilatation. When administered intravenously, losartan carboxylic acid is more potent and has a longer duration of

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Description

both of which are critical for glutamate-mediated signal transduction mechanisms

Oncol Lett

which can be significantly enhanced when combined with radiation

Smiles: CCOC(=O)C1=CC(N)=C(C=C1)NC1CCCCC1

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