GDC046 Size:100 mg solid 3 μM and in a

3 μM and in a non-competitive manner with respect to phosphatidylserine and ATP

Leuthner B

2016 Feb 12

nitric oxide-activated enzyme) that enhances the pro-apoptotic effects of cisplatin in human mesothelioma cells

GDC046 Size:100 mg solid 3 μM and in aGDC046 (Compound 3) is a potent, selective, and orally bioavailable inhibitor of TYK2 with Ki of 4. 8 nM, 83. 8 nM, 27. 6 nM and 253 nM for TYK2, JAK1, JAK2, and JAK3, respectively. Product information CAS Number: 1258292 64 6 Molecular Weight: 350. 20 Formula: C16H13Cl2N3O2 Chemical Name: 2, 6 dichloro N (2 (cyclopropanecarboxamido)pyridin 4 yl)benzamide Smiles: O=C(NC1=CC(NC(=O)C2CC2)=NC=C1)C1C(Cl)=CC=CC=1Cl InChiKey: IAFNAEGXTKTGHN UHFFFAOYSA N