BMS-911543 - CAS# 1271022-90-2 Size:Solid 10 mg InChi: InChI=1S/C19H20N4O

InChi: InChI=1S/C19H20N4O

Identification and characterization of small molecule modulators of the Epstein-Barr virus-induced gene 2 (EBI2) receptor

Dissolve 2 g of SBE-β-CD in 0

The pulse rate did not change significantly during the administration periods

BMS-911543 - CAS# 1271022-90-2 Size:Solid 10 mg InChi: InChI=1S/C19H20N4OBMS 911543 is an orally available small molecule targeting a subset of Janus associated kinase (JAK) with potential antineoplastic activity. JAK2 inhibitor BMS 911543 selectively inhibits JAK2, thereby preventing the JAK STAT (signal transducer and activator of transcription) signaling cascade, including activation of STAT3. This may lead to an induction of tumor cell apoptosis and a decrease in cellular proliferation. JAK2, often upregulated or