TRPC6 inhibitor ripenem Chemical Name: 1-(2-{[3-(2-phenylethynyl)pyrido[2
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TRPC6 inhibitor ripenem Chemical Name: 1-(2-{[3-(2-phenylethynyl)pyrido[2SAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels that opens new opportunities for the investigation of TRPC channel function in vivo. SAR7334 inhibited TRPC6, TRPC3 and TRPC7 mediated Ca(2+) influx into cells with IC50 s of 9. 5, 282 and 226 nM, whereas TRPC4 and TRPC5 mediated Ca(2+) entry was not affected. Product information CAS Number: 1333207 63 8 Molecular Weight: 440. 79 Formula: C21H24Cl3N3O Chemical Name: 4
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