Tasisulam(LY573636) - CAS# 519055-62-0 060 Hedgehog partial agonism drives Warburg-like
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Tasisulam(LY573636) - CAS# 519055-62-0 060 Hedgehog partial agonism drives Warburg-likeTasisulam, also known as LY573636, CAS No. 519055 62 0, is an acyl sulfonamide with potential antineoplastic activity. Selectively toxic towards tumor cells, tasisulam appears to induce tumor cell apoptosis by a mitochondrial targeted mechanism involving the loss of mitochondrial membrane potential and induction of reactive oxygen species (ROS). In combination with an angiogenesis inhibitor, this agent may exhibit synergistic antiangiogenic activity.
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