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P5091 - Ubiquitin-specific Protease 7 (USP7) Inhibitor. CAS# 882257-11-6 size:2 mg solid and markedly inhibits the growth

P5091 - Ubiquitin-specific Protease 7 (USP7) Inhibitor. CAS# 882257-11-6 size:2 mg solid and markedly inhibits the growth

Name: P5091 - Ubiquitin-specific Protease 7 (USP7) Inhibitor. CAS# 882257-11-6 size:2 mg solid and markedly inhibits the growth
Brand: www.coronastickers.nu
SKU: 54414033520
Price: 45.00 USD
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Rating: 4.5184 (14 reviews)

SKU: 54414033520

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P5091 - Ubiquitin-specific Protease 7 (USP7) Inhibitor. CAS# 882257-11-6 size:2 mg solid and markedly inhibits the growthP5091 (P005091), CAS No. 882257 11 6, is a novel potent and selective inhibitor of ubiquitin specific protease 7 (USP7) with an IC50 ~4. 2 M. It does not inhibit other DUBs or other families of cysteine proteases tested (EC50 > 100 mM). It induces apoptosis in MM cells resistant to conventional and bortezomib therapies. Biochemical and genetic studies showed that blockade of HDM2 and p21 abrogated P5091 induced cytotoxicity. In animal tumor model

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Description

and markedly inhibits the growth of EZH2 mutant DLBCL xenografts in mice

02 μM for Hep 3B

Chemical Name: N-(6-chlorobenzo[d]thiazol-2-yl)-3-(3

visible nuclei and more noticeable bile canaliculi between hepatocytes

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