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AMG 232 Catalog No.:M8600-10 Smiles: CC(C)(C)C1=CC(C(O)=O)=C(NC(=O)NC2C=C3C=NNC3=CC=2)S1

AMG 232 Catalog No.:M8600-10 Smiles: CC(C)(C)C1=CC(C(O)=O)=C(NC(=O)NC2C=C3C=NNC3=CC=2)S1

Name: AMG 232 Catalog No.:M8600-10 Smiles: CC(C)(C)C1=CC(C(O)=O)=C(NC(=O)NC2C=C3C=NNC3=CC=2)S1
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SKU: 57346497036
Price: 105.00 USD
Availability: InStock
Rating: 4.6993 (6 reviews)

SKU: 57346497036

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AMG 232 Catalog No.:M8600-10 Smiles: CC(C)(C)C1=CC(C(O)=O)=C(NC(=O)NC2C=C3C=NNC3=CC=2)S1AMG232 is an extremely potent MDM2 inhibitor (SPR KD = 0. 045 nM, SJSA 1 EdU IC50 = 9. 1 nM), with remarkable pharmacokinetic properties and in vivo antitumor activity in the SJSA 1 osteosarcoma xenograft model (ED50 = 9. 1 mg kg). AMG232 is currently under clinical development. Product information CAS Number: 1352066 68 2 Molecular Weight: 568. 55 Formula: C28H35Cl2NO5S Synonym: AMG232 AMG 232 Chemical Name: 2 [(3R,5R,6S) 5 (3 chlorophenyl) 6 (4

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Description

Smiles: CC(C)(C)C1=CC(C(O)=O)=C(NC(=O)NC2C=C3C=NNC3=CC=2)S1

⁸]undecan-5-yl 1H-indole-3-carboxylate

2016 Jan-Feb

InChi: InChI=1S/C11H11F3N2O3/c1-6(2)10(17)15-7-3-4-9(16(18)19)8(5-7)11(12

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