Tubastatin A Hydrochloride - CAS# 1310693-92-5 Size:Solid 10 mg leading to cell cycle arrest
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Tubastatin A Hydrochloride - CAS# 1310693-92-5 Size:Solid 10 mg leading to cell cycle arrestTubastatin A is a potent and selective HDAC6 inhibitor. Tubastatin A demonstrates 1093 fold selectivity over HDAC1 (IC50 values of 15 nM for HDAC6 vs 16. 4 M for HDAC1). Tubastatin A was substantially more selective than the known HDAC6 inhibitor Tubacin at all isozymes except HDAC8. Tubastatin A is a potent HDAC6 inhibitor with an IC50 value of 15 nM. Comparatively, it demonstrates over 1,000 fold selectivity against all other HDAC isoforms (IC50 >16
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