AT13148 - CAS# 1056901-62-2 60075 Molecular Weight: 328
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AT13148 - CAS# 1056901-62-2 60075 Molecular Weight: 328AT13148, CAS No. 1056901 62 2, is a novel oral multi AGC kinase inhibitor with potent pharmacodynamic and antitumor activity, which shows a distinct mechanism of action from other AKT inhibitors. AT13148 is currently being developed by Astex Pharmaceuticals. AT131148 was identified utilizing high throughput X ray crystallography and fragment based lead discovery techniques. AT13148 caused substantial blockade of AKT, p70S6K, PKA, ROCK and SGK
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