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A 438079 Hydrochloride - CAS# 899431-18-6 Size:Solid 2 mg CCT 241533 dihydrochloride is a

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A 438079 Hydrochloride - CAS# 899431-18-6 Size:Solid 2 mg CCT 241533 dihydrochloride is aA 438079 is a P2X7 receptor antagonist. A438079 protects against acetaminophen induced liver injury by inhibiting p450 isoenzymes, not by inflammasome activation. A 438079 partially but significantly prevented the 6 OHDA induced depletion of striatal DA stores. P2X7R inhibitor A 438079 reduced electrographic and clinical seizure severity during status epilepticus and reduced seizure induced neuronal death in the neocortex. Blockade of P2X(7) receptors

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Description

CCT 241533 dihydrochloride is a potent Chk2 inhibitor (IC50 = 3 nM)

PMID: 24321244

InChi: InChI=1S/C30H31F3N4O3/c1-3-36-10-12-37(13-11-36)18-21-6-5-20(15-25(21)30(31

AMG837 sodium salt

A 438079 Hydrochloride - CAS# 899431-18-6 Size:Solid 2 mg CCT 241533 dihydrochloride is aA 438079 is a P2X7 receptor antagonist. A438079 protects against acetaminophen induced liver injury by inhibiting p450 isoenzymes, not by inflammasome activation. A 438079 partially but significantly prevented the 6 OHDA induced depletion of striatal DA stores. P2X7R inhibitor A 438079 reduced electrographic and clinical seizure severity during status epilepticus and reduced seizure induced neuronal death in the neocortex. Blockade of P2X(7) receptors

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