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SC-79 - CAS# 305834-79-1 Catalog No.:M6552-2 Formula: C9H16Br2N5O4P

SC-79 - CAS# 305834-79-1 Catalog No.:M6552-2 Formula: C9H16Br2N5O4P

Name: SC-79 - CAS# 305834-79-1 Catalog No.:M6552-2 Formula: C9H16Br2N5O4P
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SC-79 - CAS# 305834-79-1 Catalog No.:M6552-2 Formula: C9H16Br2N5O4PSC 79, CAS No. 305834 79 1, is an activator of Akt that blocks its membrane translocation while allowing its phosphorylation, in the cytosol, by upstream kinases. SC 79 is a potential treatment for alcohol induced osteonecrosis of the femoral head. SC 79 injections inhibited alcohol induced osteonecrosis. Alcohol induced ONFH is associated with suppression of p Akt Ser473 in the Akt GSK3 catenin signaling pathway in bone mesenchymal stem cells.

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Description

Formula: C9H16Br2N5O4P

53(2):289-96

It has no effect on a panel of seven other methyltransferases

InChi: InChI=1S/C23H19NO3/c1-26-17-11-7-15(8-12-17)21(16-9-13-18(27-2)14-10-16)22-19-5-3-4-6-20(19)24-23(22)25/h3-14H

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