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TP0463518 Catalog No.:M7516-10 Chemical Name: N-(2-(4-amino-3-(p-tolyl)-1H-pyrazolo[3

SKU: 78327525940

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TP0463518 Catalog No.:M7516-10 Chemical Name: N-(2-(4-amino-3-(p-tolyl)-1H-pyrazolo[3TP0463518 is a potent hypoxia inducible factor prolyl hydroxylases (PHDs) inhibitor with Ki of 5. 3 nM for human PHD2. TP0463518 inhibits human PHD1, human PHD3 and monkey PHD2 with IC50 of 18 nM, 63 nM and 22 nM, respectively. Product information CAS Number: 1558021 37 6 Molecular Weight: 431. 83 Formula: C20H18ClN3O6 Chemical Name: (1 ((6 (4 chlorophenoxy)pyridin 3 yl)methyl) 4 hydroxy 2 oxo 1, 2, 5, 6 tetrahydropyridine 3 carbonyl)glycine Smiles:

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Description

Chemical Name: N-(2-(4-amino-3-(p-tolyl)-1H-pyrazolo[3

PMID: 31792121

elevated global levels of H3K4 trimethylation (H3K4me3) and decreased the number of DTPs in multiple cancer cell line models treated with standard chemotherapy or targeted agents

targeting Akt1

TP0463518 Catalog No.:M7516-10 Chemical Name: N-(2-(4-amino-3-(p-tolyl)-1H-pyrazolo[3TP0463518 is a potent hypoxia inducible factor prolyl hydroxylases (PHDs) inhibitor with Ki of 5. 3 nM for human PHD2. TP0463518 inhibits human PHD1, human PHD3 and monkey PHD2 with IC50 of 18 nM, 63 nM and 22 nM, respectively. Product information CAS Number: 1558021 37 6 Molecular Weight: 431. 83 Formula: C20H18ClN3O6 Chemical Name: (1 ((6 (4 chlorophenoxy)pyridin 3 yl)methyl) 4 hydroxy 2 oxo 1, 2, 5, 6 tetrahydropyridine 3 carbonyl)glycine Smiles:

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