Mometasone furoate estrol (aglycone) AUCINF=295 hr*ng/ml)

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Mometasone furoate estrol (aglycone) AUCINF=295 hr*ng/ml)Like other topical corticosteroids, mometasone furoate has anti inflammatory, antipruritic, and vasoconstrictive properties. The mechanism of the anti inflammatory activity of the topical steroids, in general, is unclear. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation

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